Preheat oven to 350 degrees F. Line a large baking sheet with parchment paper and set aside.
In a medium bowl, whisk together the 3 cups all-purpose flour, 1 ½ teaspoons baking powder, 1 teaspoon baking soda, and 1 teaspoon salt. This step is optional and does add an additional bowl, but helps the process become more seamless.
Using an electric hand mixer or stand mixer, cream together the 1 cup butter, ½ cup granulated sugar, and 1 ½ cups brown sugar until it is light and fluffy.
Add in the 2 eggs, 2 teaspoons vanilla extract, and mix until combined. Turn the mixer down on low speed and slowly add in the flour mixture.
Fold in the 1 ½ cups chocolate chips and 1 cup chopped pretzels. Form the cookies into balls or use a cookie scoop of your preferred size and place on the prepared baking sheet. Press the cookies in the center to flatten them out a bit.
Place the cookies into the preheated oven and bake for cookies 10 to 12 minutes or until the edges are golden brown.
Carefully remove the cookies from the oven and allow them to cool on the baking sheet for 2 to 3 minutes before transferring to a wire rack to cool completely. Store the cookies in an airtight container at room temperature up to 5 days.