Begin the recipe by preheating the oven to 350 degrees F. Using a large mixing bowl add the 6 slices of bread and 1 cup milk. Allow time for the milk to soak into the bread about 2 to 3 minutes.
To the same bowl, add the 1 pound ground beef, 1 pound ground pork, 1 cup Parmesan cheese, ⅓ cup onion, ¾ cup green bell pepper, ⅓ cup chopped Italian parsley, ¼ teaspoon seasoned salt, ¾ teaspoon salt, and ½ teaspoon ground black pepper. Stir to combine.
Lightly beat the 4 large eggs and add them to the bowl with the other ingredients. Using clean or gloved hands, mix the ingredients until well combined. The meat mixture should be able to form into a loaf.
Remove the meatloaf mixture from the bowl and add it to a baking pan, broiler pan, or sheet pan (lined with aluminum foil). Use your hands to form the mixture into a loaf shape. Set aside.
Using a small bowl, whisk together the 1 ½ cups ketchup, ⅓ cup brown sugar, 1 teaspoon mustard, and ¼ teaspoon hot sauce until combined. Spread about ⅓ of the sauce evenly on top of the uncooked meatloaf. Place into the preheated oven to bake for 45 minutes.
Carefully remove the meatloaf from the oven and evenly spread another layer, about half of the sauce that is left, over the top of the cooked meatloaf. Place the meatloaf back into the oven and continue baking for about 15 to 20 minutes, until the internal temperature reaches 160 degrees F.
Carefully remove the fully cooked meatloaf from the oven and serve warm with the remaining sauce. Try pairing it with mashed potatoes for a complete and comforting family dinner. Enjoy!